Portfolio

To address AMR and protect the lives of people around the world, PACE is providing funding and support for a portfolio of early-stage projects to help grow the pipeline of high-quality antimicrobial therapeutics and associated diagnostics.

Supporting the best innovations to address the global threat of AMR

We are supporting a diverse portfolio of projects aimed at developing new tests and treatments for bacterial infections with high unmet need. Through a series of funding rounds available to academics and SMEs worldwide, we are selecting, investing in and supporting the most promising projects. We are offering a collaborative approach to project development through access to advisors, mentors, potential project partners and enabling technologies and capabilities. By supporting the projects in this way, we are helping to give them the best chance of success and position them for onward funding, investment and development. More projects will enter the portfolio as the programme progresses. This page highlights the innovators and projects that are currently in the PACE portfolio.

11

Number of projects supported

£11m

PACE funds committed to projects

12

Number of organisations funded

Portfolio Projects


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ArrePath

Project title: Advancing a direct-acting, small molecule antibacterial with Gram negative specificity and a novel mechanism of action


Centauri Therapeutics

Project title: Optimisation of rhamnose presentation for next generation Alphamers® for the treatment of Gram-negative infections


Glox Therapeutics

Project title: Precision antibiotics for Enterobacteriaceae


Immunethep

Project title: Monoclonal antibodies targeting bacterial GAPDH as a single immunotherapy to treat infections caused by E. coli and Klebsiella pneumoniae


Ineos Oxford Institute of Antimicrobial Research

Project title: Next generation, broad spectrum cell wall targeting antibiotics


Justus Liebig University Giessen (JLU) and Infex Therapeutics

Project title: Novel drugs against Gram-negative bacterial pathogens


Oxford Drug Design

Project title: Leucyl-tRNA synthetase inhibitor for oral therapy of urinary tract infections


PhalconBio

Project title: Engineered Phage Therapeutics (EPTs) to treat P. aeruginosa infections in bronchiectasis patients


The Geneva Foundation with Triari Pharmaceuticals

Project title: Lead optimisation of mAbs targeting Acinetobacter baumannii iron acquisition proteins